principal investigator

Image of Edward Ruby

Edward (Ned) Ruby

Pacific Biosciences Research Center
Phone: (808) 539-7300
Dr. Ruby has worked for 30 years on beneficial bacterial-host interactions. He was hired into the Symbiosis Cluster at the University of Wisconsin-Madison in 2004, where he held the Steenbock Chair of Microbiological Sciences, and was Vice-Chair of the Department of Medical Microbiology & Immunology. He has served on the Board of Governors of the American Academy of Microbiology; has been a visiting professor at HuaZhong U, China and a EU/Marie Curie ITN Researcher at the Max-Planck Institute, Bremen, Germany; and has received the University of Hawaii’s Regents Medal for Excellence in Research. Recently, he was a Moore Scholar at the California Institute of Technology, and was Chair of the American Academy of Microbiology Awards Board. With Nicole Dubilier, he instituted and chaired the Gordon Research Conference on Animal-Microbe Symbioses, and is currently directing the annual West Coast Bacterial Physiologists Conference at Asilomar, CA. He currently co-directs the NIH-COBRE Integrative Center for Environmental Microbiomes and Human Health.

In 2015, Dr. Ruby moved his lab back to the University of Hawaii-Manoa. His current research uses (i) a broad-based approach to analyze how sequential signaling cascades and nutrient manipulation produce rhythmic patterns of bacterial metabolism that underlie the association’s persistence, (ii) new analytical and imaging approaches to discover novel pathways of signaling between the symbiont and its host, and (iii) comparative and functional genomics and epigenetics to discover principles controlling population-level interactions among symbionts.